Information and support for people living with CRPS
Understand CRPS, learn what the scientific literature says about neridronate, explore treatment possibilities and get direct support to identify the path that best fits your needs.
Clear sources, understandable information and careful research.
CRPS, neridronate possibilities, science and practical guidance in one place.
CRPS can affect pain, movement, sleep, work, relationships and mental wellbeing. CRPS Support brings the most important questions together so patients and families can move from confusion to a clearer plan.
Symptoms, diagnosis, disease phases and the difference between CRPS-I and CRPS-II.
Neridronate is a bisphosphonate that has been studied in CRPS-I and is used for the treatment of CRPS. The scientific area of CRPS Support brings together studies, regulatory documents and practical explanations for patients and families.
Neridronate Treatment Approval
Official information about the use of neridronate for CRPS.
The dedicated library will organize peer-reviewed studies, official documents and treatment information so patients can understand the evidence and bring informed questions to their healthcare team.
Research papers and study summaries
Regulatory and prescribing information
Its development is supported not only by clinical studies, but also by CRPS-specific U.S. patent protection covering neridronic-acid treatment methods and formulations, plus FDA Breakthrough Therapy, Fast Track and Orphan Drug designations. The pivotal CRPS-RISE Phase 3 program is now underway.
A second placebo-controlled study again showed a clinically relevant treatment signal, including a much higher ≥50% pain-responder rate.
Multiple granted U.S. patents cover neridronic-acid methods and molecular complexes for treating CRPS and CRPS-related symptoms.
Neridronate is not currently FDA-approved for CRPS in the United States. FDA designations and Phase 3 development are not the same as marketing approval.
Compare the main treatment settings currently identified by CRPS Support. Each facility has a different care model, level of logistical support and route of access, especially for patients travelling from abroad.
Private pathway in Rome dedicated to Neridronate treatment for CRPS, at Via degli Uffici del Vicario 33.
University-hospital option in Sicily included in the CRPS Support list of Italian Neridronate treatment facilities.
Carla Crowe can help you organize the practical questions to ask each facility and understand which route may better fit your timing, travel needs and personal situation.
Behind every diagnosis there is a person who wants to return to everyday life. These photographs capture different moments in real patient journeys—from treatment days to the moments that come after.
Our mission is to help people living with CRPS understand the possibilities available to them and identify the treatment path that best fits their clinical situation, priorities, practical needs and personal circumstances.
We bring together scientific information, treatment possibilities and direct patient support so each person can ask better questions, compare options and move toward a solution with greater clarity and confidence.
Have questions about CRPS, neridronate or treatment possibilities? Send us a message. Carla Crowe and the CRPS Support team can help you find the information most useful for your situation and understand the next practical steps.
