Navigating Your CRPS Journey: From Diagnosis to Remission in Italy
Living with Complex Regional Pain Syndrome (CRPS)—formerly known as RSD—often feels like an endless cycle of “managing” pain without ever actually defeating it. For many Americans, the standard path involves high-dose opioids, invasive spinal stimulators, or ketamine infusions that offer only fleeting relief.
At CRPS-Support, we believe your journey should lead to a destination: remission. By bridging the gap between California and the world-class medical facilities in Italy, we help you access Neridronate infusions, the only pharmaceutical treatment scientifically proven to target the root cause of CRPS.
The Road Map: Understanding Your CRPS Journey
The path to recovery isn’t just about a single infusion; it’s a comprehensive 360° approach that addresses the physical, neurological, and nutritional aspects of the disease.
1. Expert Diagnosis & Eligibility
The first hurdle is often getting a “certified” diagnosis. Many doctors are unfamiliar with the Budapest Criteria, the international standard for identifying CRPS.
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Local Support: Our California-based coordinators, Nicolò Cladera and Carla Crowe, act as your primary points of contact. They help gather your medical history and specific blood tests (including Calcium, Vitamin D, and Creatinine levels) required by Italian specialists to confirm your eligibility.
2. Treating the Root Cause with Neridronate
While US treatments often focus on masking pain, the Italian protocol utilizes Neridronate infusions to treat the underlying bone edema and inflammatory cytokines.
The Protocol: This involves four intravenous infusions over ten days.
The Goal: Unlike temporary anesthetics, Neridronate is a one-time treatment designed for permanent results. In clinical trials, patients reported total symptom remission one year after the infusions.
3. Multidisciplinary Rehabilitation in Italy
Recovery doesn’t stop at the infusion. To regain full function, we coordinate a suite of specialized therapies:
Neuromuscular Re-education: Retraining your brain and body to move normally after months or years of “pain-guarding”.
Biophysical & Light Therapy: Using advanced wave frequencies and wavelengths to stimulate cellular repair and boost immune function.
Nutritional Support: Addressing gut dysbiosis, which is scientifically linked to chronic pain and inflammation.
Why Travel to Italy for Treatment?
Italy is currently the global leader in CRPS care. While Phase 3 trials for Neridronate in the US faced administrative halts in 2019, the Italian Drug Agency (AIFA) has recognized it as the standard of care since 2016.
| Feature | US Standard Care | Neridronate (Italy) |
| Primary Goal |
Pain Management
|
Disease Remission
|
| Duration |
Lifelong medications
|
4 Infusions (One-time)
|
| Invasiveness |
Spinal Cord Stimulators/Pumps
|
Non-invasive IV Infusions
|
| Side Effects |
Addiction, Cognitive issues
|
Short-term flu-like symptoms |

